Citations for Evidence-Based Practices on Foundational Nutrional Science

Seed & Stone Nutrional Therapy Guiding Evidence-Based Practices

At Seed & Stone Nutritional Therapy, our approach is rooted in evidence-informed Nutritional Therapy practices. Jean Patton, NTP, does not diagnose or treat medical conditions. Instead, she provides personalized guidance based on established nutritional and lifestyle principles designed to support the body’s foundational health.

Our recommendations are informed by peer-reviewed research in Clinical Nutrition, Nutritional Science, and Lifestyle Medicine. We prioritize high-quality scientific evidence, including research indexed in PubMed, to guide the programs and resources we offer.

Nutrition & Chronic Disease

• Schwingshackl L, et al. (2017). Food groups and risk of chronic disease: a systematic review and meta-analysis of prospective studies. https://pubmed.ncbi.nlm.nih.gov/28446499/
• Mozaffarian D. (2016). Dietary and policy priorities for cardiovascular disease, diabetes, and obesity. https://pubmed.ncbi.nlm.nih.gov/26746178/
• Estruch R, et al. (2018). Primary prevention of cardiovascular disease with a Mediterranean diet. https://pubmed.ncbi.nlm.nih.gov/29897866/
• Szczerba E, et al. (2023). Diet in the management of type 2 diabetes: an umbrella review of systematic reviews with meta-analyses of randomized controlled trials. https://pubmed.ncbi.nlm.nih.gov/38027413/
• Ni C, et al. (2022). Low-glycemic index diets as an intervention in metabolic diseases: a systematic review and meta-analysis. https://pubmed.ncbi.nlm.nih.gov/35057488/

Nutrition & Inflammation

• Calder PC, et al. (2017). Dietary factors and low-grade inflammation in relation to overweight and obesity. https://pubmed.ncbi.nlm.nih.gov/28507012/
• Aleksandrova K, et al. (2021). Dietary patterns, oxidative stress, and inflammation: a systematic review and meta-analysis. https://pubmed.ncbi.nlm.nih.gov/39940408/
• Wastyk HC, et al. (2021). The effect of dietary interventions on chronic inflammatory diseases in relation to the microbiome: a systematic review. https://pubmed.ncbi.nlm.nih.gov/34579085/
• Wu PY, et al. (2021). The Mediterranean dietary pattern and inflammation in older adults: a systematic review and meta-analysis. https://pubmed.ncbi.nlm.nih.gov/33002104/
• Hart MJ, et al. (2021). Dietary patterns and associations with biomarkers of inflammation in adults: a systematic review of observational studies. https://pubmed.ncbi.nlm.nih.gov/33712009/

Gut Health & Microbiome

• Thursby E, Juge N. (2017). Introduction to the human gut microbiota. https://pubmed.ncbi.nlm.nih.gov/28512250/
• Valdes AM, Walter J, Segal E, Spector TD. (2018). Role of the gut microbiota in nutrition and health. https://pubmed.ncbi.nlm.nih.gov/29899036/
• Zhang, Ping. (2022) Influence of Foods and Nutrition on the Gut Microbiome and Implications for Intestinal Health. https://pubmed.ncbi.nlm.nih.gov/36076980/
• Wiertsema SP, van Bergenhenegouwen J, Garssen J, Knippels LMJ. (2021). The Interplay between the Gut Microbiome and the Immune System in the Context of Infectious Diseases throughout Life and the Role of Nutrition in Optimizing Treatment Strategies. https://pubmed.ncbi.nlm.nih.gov/33803407/
• Ross, Fiona C., et al. (2024). The interplay between diet and the gut microbiome: implications for health and disease. https://pubmed.ncbi.nlm.nih.gov/39009882/

Blood Sugar Regulation

• Evert AB, et al. (2019). Nutrition therapy for adults with diabetes or prediabetes: a consensus report. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7011201/
• Sainsbury E, et al. (2018). Effect of dietary carbohydrate restriction on glycemic control in adults with diabetes: a systematic review and meta-analysis. https://pubmed.ncbi.nlm.nih.gov/29522789/
• Esposito K, et al. (2010). Prevention and control of type 2 diabetes by Mediterranean diet: a systematic review. https://pubmed.ncbi.nlm.nih.gov/20546959/
• Accurso A, et al. (2008). Dietary carbohydrate restriction in type 2 diabetes mellitus and metabolic syndrome: time for a critical appraisal. https://pubmed.ncbi.nlm.nih.gov/18397522/
• Russell WR, et al. (2013). Impact of diet composition on blood glucose regulation. https://pubmed.ncbi.nlm.nih.gov/24219323/

Nutrition, Sleep & Stress

• Zuraikat FM, et al. (2021). Sleep and diet: mounting evidence of a cyclical relationship. https://pubmed.ncbi.nlm.nih.gov/34348025/
• Coxon C, Nishihira J, Hepsomali P. (2024). Dietary inflammatory index, sleep duration, and sleep quality: a systematic review. https://pubmed.ncbi.nlm.nih.gov/38542801/
• Golmohammadi M, et al. (2024). The association of dietary inflammatory index with sleep outcomes: a systematic review. https://pubmed.ncbi.nlm.nih.gov/39291049/
• Arab A, et al. (2025). Sleep and the Mediterranean diet: a systematic review and meta‑analysis. https://pubmed.ncbi.nlm.nih.gov/40081182/
• Binks H, et al. (2020). Effects of diet on sleep: a narrative review. https://pubmed.ncbi.nlm.nih.gov/32230944/